Anxiolytic effects of Dolichandrone falcata Seem., Bignoniaceae, stem-bark in elevated plus maze and marble burying test on mice
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Potential antioxidant and anxiolytic effects of (+)-limonene epoxide in mice after marble-burying test
The present study evaluated anxiolytic activity of (+)-limonene epoxide (EL), through the marble burying test (MBT) assay, and the antioxidant potential in vitro and in vivo in mice hippocampus of adult mice subjected to experimental anxiety protocol. For behavioral studies, and in vivo antioxidant analyses, mice were treated orally with 0.05% Tween 80 dissolved in 0.9% saline solution (vehicle...
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Introduction: Sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, may have various effects on the central nervous system via the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway. Preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals. This study was undertaken to investigate the acute effect of sildenafil on anxiety-like behavior...
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ژورنال
عنوان ژورنال: Revista Brasileira de Farmacognosia
سال: 2010
ISSN: 0102-695X
DOI: 10.1590/s0102-695x2010005000028